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Prognostic prediction of glioblastoma by quantitative assessment of the methylation status of the entire MGMT promoter region
BACKGROUND: O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation is reported to be a prognostic and predictive factor of alkylating chemotherapy for glioblastoma patients. Methylation specific PCR (MSP) has been most commonly used when the methylation status of MGMT is assessed. Howeve...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
BioMed Central
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4161852/ https://ncbi.nlm.nih.gov/pubmed/25175833 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-641 |
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