Impact of KIT exon 10 M541L allelic variant on the response to imatinib in aggressive fibromatosis: analysis of the desminib series by competitive allele specific Taqman PCR technology

BACKGROUND: Aggressive fibromatosis (AF) is a rare fibroblastic proliferative disease with a locally aggressive behavior and no distant metastasis, characterized by driver mutations in CTNNB1 or the APC gene. When progressive and/or symptomatic AF is not amenable to local management, a variety of me...

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Bibliographic Details
Main Authors: Dufresne, Armelle, Alberti, Laurent, Brahmi, Mehdi, Kabani, Sarah, Philippon, Héloïse, Pérol, David, Blay, Jean Yves
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4161827/
https://ncbi.nlm.nih.gov/pubmed/25174682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-632
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