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Specific tumor labeling enhanced by polyethylene glycol linkage of near infrared dyes conjugated to a chimeric anti-carcinoembryonic antigen antibody in a nude mouse model of human pancreatic cancer

Labeling of metastatic tumors can aid in their staging and resection of cancer. Near infrared (NIR) dyes have been used in the clinic for tumor labeling. However, there can be a nonspecific uptake of dye by the liver, lungs, and lymph nodes, which hinders detection of metastasis. In order to overcom...

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Detaylı Bibliyografya
Asıl Yazarlar: Maawy, Ali A., Hiroshima, Yukihiko, Zhang, Yong, Luiken, George A., Hoffman, Robert M., Bouvet, Michael
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Society of Photo-Optical Instrumentation Engineers 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160999/
https://ncbi.nlm.nih.gov/pubmed/24887695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1117/1.JBO.19.10.101504
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