The Achievement of a 3-Month Complete Cytogenetic Response to Second-Generation Tyrosine Kinase Inhibitors Predicts Survival in Patients With Chronic Phase Chronic Myeloid Leukemia After Imatinib Failure

To evaluate the importance of achieving a CCyR for CML patients failing imatinib and treated with 2nd generation TKI’s, we studied the effect of CCyR on OS in 123 CP CML patients failing frontline imatinib treatment. We found that achieving CCyR at 3 months is the only predictive factor of good outc...

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Detalhes bibliográficos
Main Authors: Jabbour, Elias, Kantarjian, Hagop, Ghanem, Hady, O’Brien, Susan, Quintas-Cardama, Alfonso, Garcia-Manero, Guillermo, Cardenas, Marylou, Cortes, Jorge
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160838/
https://ncbi.nlm.nih.gov/pubmed/23318257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clml.2012.12.005
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