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The Achievement of a 3-Month Complete Cytogenetic Response to Second-Generation Tyrosine Kinase Inhibitors Predicts Survival in Patients With Chronic Phase Chronic Myeloid Leukemia After Imatinib Failure

To evaluate the importance of achieving a CCyR for CML patients failing imatinib and treated with 2nd generation TKI’s, we studied the effect of CCyR on OS in 123 CP CML patients failing frontline imatinib treatment. We found that achieving CCyR at 3 months is the only predictive factor of good outc...

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Bibliografiska uppgifter
Huvudupphovsmän: Jabbour, Elias, Kantarjian, Hagop, Ghanem, Hady, O’Brien, Susan, Quintas-Cardama, Alfonso, Garcia-Manero, Guillermo, Cardenas, Marylou, Cortes, Jorge
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160838/
https://ncbi.nlm.nih.gov/pubmed/23318257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clml.2012.12.005
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