Improved productivity of poly (4-hydroxybutyrate) (P4HB) in recombinant Escherichia coli using glycerol as the growth substrate with fed-batch culture

BACKGROUND: The most successful polyhydroxyalkanoate (PHA) in medical applications is poly(4-hydroxybutyrate) (P4HB), which is due to its biodegradability, biocompatibility and mechanical properties. One of the major obstacles for wider applications of P4HB is the cost of production and purification...

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Bibliografski detalji
Glavni autori: Le Meur, Sylvaine, Zinn, Manfred, Egli, Thomas, Thöny-Meyer, Linda, Ren, Qun
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160554/
https://ncbi.nlm.nih.gov/pubmed/25176327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-014-0131-2
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