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Evaluation of the kinetics and mechanism of action of anti-integration host factor mediated disruption of bacterial biofilms

The extracellular polymeric substance produced by many human pathogens during biofilm formation often contains extracellular DNA (eDNA). Strands of bacterial eDNA within the biofilm matrix can occur in a lattice-like network wherein a member of the DNABII family of DNA-binding proteins is positioned...

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Autors principals: Brockson, M. Elizabeth, Novotny, Laura A., Mokrzan, Elaine M., Malhotra, Sankalp, Jurcisek, Joseph A., Akbar, Rabia, Devaraj, Aishwarya, Goodman, Steven D., Bakaletz, Lauren O.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160410/
https://ncbi.nlm.nih.gov/pubmed/25069521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12735
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