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Cryoprotection of Lipid Membranes for High-Resolution Solid-State NMR Studies of Membrane Peptides and Proteins at Low Temperature

Solid-state NMR spectra of membrane proteins often show significant line broadening at cryogenic temperatures. Here we investigate the effects of several cryoprotectants to preserve the spectral resolution of lipid membranes and membrane peptides at temperatures down to ~200 K. Trehalose, glycerol,...

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Detalhes bibliográficos
Main Authors: Lee, Myungwoon, Hong, Mei
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160392/
https://ncbi.nlm.nih.gov/pubmed/25015530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-014-9845-z
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