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Depletion of Inflammatory Dendritic Cells with Anti-CD209 Conjugated to Saporin Toxin

Monocytes rapidly infiltrate inflamed tissues and differentiate into CD209(+) inflammatory dendritic cells (DCs) that promote robust immunity or, if unregulated, inflammatory disease. Previous studies in experimental animal models indicate that inflammatory DC depletion through systemic elimination...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Alonso, Michael N., Gregorio, Josh G., Davidson, Matthew G., Gonzalez, Joseph, Engleman, Edgar G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160227/
https://ncbi.nlm.nih.gov/pubmed/24781193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12026-014-8511-6
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