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Methyl protodioscin induces G2/M cell cycle arrest and apoptosis in A549 human lung cancer cells

BACKGROUND: Methyl protodioscin (MPD) is a furostanol bisglycoside with antitumor properties. It has been shown to reduce proliferation, cause cell cycle arrest. OBJECTIVE: The present study elucidates the mechanism underlying MPD's apoptotic effects, using the A549 human lung cancer cell line....

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Detalhes bibliográficos
Main Authors: Bai, Yang, Qu, Xiao-Yuan, Yin, Jun-Qiang, Wu, Liangcai, Jiang, Hong, Long, Han-Wu, Jia, Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159926/
https://ncbi.nlm.nih.gov/pubmed/25210320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0973-1296.137373
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