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Polymorphism of the Flap Endonuclease 1 Gene in Keratoconus and Fuchs Endothelial Corneal Dystrophy

Oxidative stress is implicated in the pathogenesis of many diseases, including serious ocular diseases, keratoconus (KC) and Fuchs endothelial corneal dystrophy (FECD). Flap endonuclease 1 (FEN1) plays an important role in the repair of oxidative DNA damage in the base excision repair pathway. We de...

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Detalhes bibliográficos
Main Authors: Wojcik, Katarzyna A., Synowiec, Ewelina, Polakowski, Piotr, Głowacki, Sylwester, Izdebska, Justyna, Lloyd, Sophie, Galea, Dieter, Blasiak, Janusz, Szaflik, Jerzy, Szaflik, Jacek P.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159882/
https://ncbi.nlm.nih.gov/pubmed/25153632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms150814786
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