Matrilin-3 Chondrodysplasia Mutations Cause Attenuated Chondrogenesis, Premature Hypertrophy and Aberrant Response to TGF-β in Chondroprogenitor Cells

Studies have shown that mutations in the matrilin-3 gene (MATN3) are associated with multiple epiphyseal dysplasia (MED) and spondyloepimetaphyseal dysplasia (SEMD). We tested whether MATN3 mutations affect the differentiation of chondroprogenitor and/or mesenchymal stem cells, which are precursors...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Jayasuriya, Chathuraka T., Zhou, Fiona H., Pei, Ming, Wang, Zhengke, Lemme, Nicholas J., Haines, Paul, Chen, Qian
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159868/
https://ncbi.nlm.nih.gov/pubmed/25196597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms150814555
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker