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Mammalian Cytochrome P450-Dependent Metabolism of Polychlorinated Dibenzo-p-dioxins and Coplanar Polychlorinated Biphenyls

Polychlorinated dibenzo-p-dioxins (PCDDs) and coplanar polychlorinated biphenyls (PCBs) contribute to dioxin toxicity in humans and wildlife after bioaccumulation through the food chain from the environment. The authors examined human and rat cytochrome P450 (CYP)-dependent metabolism of PCDDs and P...

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Detalhes bibliográficos
Main Authors: Inui, Hideyuki, Itoh, Toshimasa, Yamamoto, Keiko, Ikushiro, Shin-Ichi, Sakaki, Toshiyuki
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159838/
https://ncbi.nlm.nih.gov/pubmed/25123135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms150814044
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