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Dose-Dependent Protective Effect of Lithium Chloride on Retinal Ganglion Cells Is Interrelated with an Upregulated Intraretinal BDNF after Optic Nerve Transection in Adult Rats

Neuroprotection of lithium for axotomized retinal ganglion cells (RGCs) is attributed to upregulated intraretinal Bcl-2. As lithium also upregulates brain-derived neurotrophic factor (BDNF) which can rescue axotomized RGCs, it is hypothesized that lithium could protect RGCs through BDNF. This study...

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Detalhes bibliográficos
Main Authors: Wu, Ming-Mei, Zhu, Ting-Ting, Wang, Peng, Kuang, Fang, Hao, Ding-Jun, You, Si-Wei, Li, Yao-Yu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159810/
https://ncbi.nlm.nih.gov/pubmed/25100168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms150813550
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