Voluntary Intravenous Self-administration of Alcohol Detects an Interaction between GABAergic Manipulation and GABRG1 Polymorphism Genotype: A Pilot Study

BACKGROUND: Operant responding paradigms quantify a subject’s motivation for reward, but such studies employing ingested alcohol cannot assure the same incremental increase in brain exposure to alcohol across subjects because of substantial variability in absorption kinetics. We developed a human pr...

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Главные авторы: Plawecki, MH, Wetherill, L, Vitvitskiy, V, Kosobud, A, Zimmermann, US, Edenberg, HJ, O’Connor, S
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159724/
https://ncbi.nlm.nih.gov/pubmed/22817768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1530-0277.2012.01885.x
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