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The splicing factor RBM4 controls apoptosis, proliferation, and migration to suppress tumor progression

Splicing dysregulation is one of the molecular hallmarks of cancer. However, the underlying molecular mechanisms remain poorly defined. Here we report the splicing factor RBM4 suppresses proliferation and migration of various cancer cells by specifically controlling cancer-related splicing. Particul...

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Detalhes bibliográficos
Main Authors: Wang, Yang, Chen, Dan, Qian, Haili, Tsai, Yihsuan S., Shao, Shujuan, Liu, Quentin, Dominguez, Daniel, Wang, Zefeng
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159621/
https://ncbi.nlm.nih.gov/pubmed/25203323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2014.07.010
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