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TNF-α augmented Porphyromonas gingivalis invasion in human gingival epithelial cells through Rab5 and ICAM-1

BACKGROUND: Tumor necrosis factor alpha (TNF-α) plays a central role in the initiation and maintenance of immune responses to periodontopathic bacteria. However, excess TNF-α leads to dysregulated immune responses and progression of periodontitis. Porphyromonas gingivalis (P. gingivalis) invades gin...

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Detalhes bibliográficos
Main Authors: Kato, Yoshiko, Hagiwara, Makoto, Ishihara, Yuichi, Isoda, Ryutaro, Sugiura, Shinsuke, Komatsu, Toshinori, Ishida, Naoyuki, Noguchi, Toshihide, Matsushita, Kenji
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159534/
https://ncbi.nlm.nih.gov/pubmed/25179218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-014-0229-z
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