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DAP12 impacts trafficking and surface stability of killer immunoglobulin-like receptors on natural killer cells

KIR aid in the regulation of NK cell activity. In this study, the effect of the interaction between the KIR2DS and their adapter, DAP12, was investigated beyond the previously defined signaling function. Flow cytometry analysis showed enhanced KIR2DS surface expression on NKL cells when cotransfecte...

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Autori principali: Mulrooney, Tiernan J., Posch, Phillip E., Hurley, Carolyn Katovich
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Leukocyte Biology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159499/
https://ncbi.nlm.nih.gov/pubmed/23715743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0213093
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