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Non-canonical Wnt4 prevents skeletal aging and inflammation by inhibiting NF-κB

Aging-related bone loss and osteoporosis affect millions of patients worldwide. Chronic inflammation associated with aging and arthritis promotes bone resorption and impairs bone formation. Here we show that Wnt4 attenuated bone loss in osteoporosis and skeletal aging by inhibiting nuclear factor-ka...

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Detalhes bibliográficos
Main Authors: Yu, Bo, Chang, Jia, Liu, Yunsong, Li, Jiong, Kevork, Kareena, Al-Hezaimi, Khalid, Graves, Dana T, Park, No-Hee, Wang, Cun-Yu
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159424/
https://ncbi.nlm.nih.gov/pubmed/25108526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3586
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