Mechanism of the pH-Induced Conformational Change in the Sensor Domain of the DraK Histidine Kinase via the E83, E105, and E107 Residues

The DraR/DraK two-component system was found to be involved in the differential regulation of antibiotic biosynthesis in a medium-dependent manner; however, its function and signaling and sensing mechanisms remain unclear. Here, we describe the solution structure of the extracellular sensor domain o...

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Detalhes bibliográficos
Main Authors: Yeo, Kwon Joo, Hong, Young-Soo, Jee, Jun-Goo, Lee, Jae Kyoung, Kim, Hyo Jeong, Park, Jin-Wan, Kim, Eun-Hee, Hwang, Eunha, Kim, Sang-Yoon, Lee, Eun-Gyeong, Kwon, Ohsuk, Cheong, Hae-Kap
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159317/
https://ncbi.nlm.nih.gov/pubmed/25203403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107168
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