Endobronchial miRNAs as biomarkers in lung cancer chemoprevention

Lung cancers express lower levels of prostacyclin than normal lung tissues. Prostacyclin prevents lung cancer in a variety of mouse models. A randomized phase II trial comparing oral iloprost (a prostacyclin analogue) to placebo in high-risk subjects demonstrated improvement in bronchial histology i...

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Autori principali: Mascaux, Celine, Feser, William J, Lewis, Marina T, Barón, Anna E, Coldren, Christopher D, Merrick, Daniel T, Kennedy, Timothy C, Eckelberger, John I, Rozeboom, Leslie M, Franklin, Wilbur A, Minna, John D, Bunn, Paul A, Miller, York E, Keith, Robert L, Hirsch, Fred R
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159305/
https://ncbi.nlm.nih.gov/pubmed/23268837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-12-0382
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