Endobronchial miRNAs as biomarkers in lung cancer chemoprevention

Lung cancers express lower levels of prostacyclin than normal lung tissues. Prostacyclin prevents lung cancer in a variety of mouse models. A randomized phase II trial comparing oral iloprost (a prostacyclin analogue) to placebo in high-risk subjects demonstrated improvement in bronchial histology i...

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Autors principals: Mascaux, Celine, Feser, William J, Lewis, Marina T, Barón, Anna E, Coldren, Christopher D, Merrick, Daniel T, Kennedy, Timothy C, Eckelberger, John I, Rozeboom, Leslie M, Franklin, Wilbur A, Minna, John D, Bunn, Paul A, Miller, York E, Keith, Robert L, Hirsch, Fred R
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159305/
https://ncbi.nlm.nih.gov/pubmed/23268837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-12-0382
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