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Mechanistic Evaluation of the Ni(IPr)(2)−Catalyzed Cycloaddition of Alkynes and Nitriles to Afford Pyridines: Evidence for the Formation of a Key η(1)−Ni(IPr)(2)(RCN) Intermediate

A detailed mechanistic evaluation of the Ni(IPr)(2)-catalyzed [2+2+2]-cycloaddition of diynes and nitriles was 2 conducted. Through kinetic analysis of these reactions, observed regioselectivities of the products, and stoichiometric reactions, Ni(IPr)(2)-catalyzed cycloadditions of diynes and nitril...

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Autors principals: Stolley, Ryan M., Duong, Hung A., Louie, Janis
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159214/
https://ncbi.nlm.nih.gov/pubmed/25214702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/om400666k
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