Abundant local interactions in the 4p16.1 region suggest functional mechanisms underlying SLC2A9 associations with human serum uric acid

Human serum uric acid concentration (SUA) is a complex trait. A recent meta-analysis of multiple genome-wide association studies (GWAS) identified 28 loci associated with SUA jointly explaining only 7.7% of the SUA variance, with 3.4% explained by two major loci (SLC2A9 and ABCG2). Here we examined...

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Bibliographic Details
Main Authors: Wei, Wen-Hua, Guo, Yunfei, Kindt, Alida S.D., Merriman, Tony R., Semple, Colin A., Wang, Kai, Haley, Chris S.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159153/
https://ncbi.nlm.nih.gov/pubmed/24821702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu227
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