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TDP-43 suppresses CGG repeat-induced neurotoxicity through interactions with HnRNP A2/B1
Nucleotide repeat expansions can elicit neurodegeneration as RNA by sequestering specific RNA-binding proteins, preventing them from performing their normal functions. Conversely, mutations in RNA-binding proteins can trigger neurodegeneration at least partly by altering RNA metabolism. In Fragile X...
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| Asıl Yazarlar: | , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Oxford University Press
2014
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4159148/ https://ncbi.nlm.nih.gov/pubmed/24920338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu216 |
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