Regional Fluid-Attenuated Inversion Recovery (FLAIR) at 7 Tesla correlates with amyloid beta in hippocampus and brainstem of cognitively normal elderly subjects

Background: Accumulation of amyloid beta (Aβ) may occur during healthy aging and is a risk factor for Alzheimer Disease (AD). While individual Aβ-accumulation can be measured non-invasively using Pittsburgh Compund-B positron emission tomography (PiB-PET), Fluid-attenuated inversion recovery (FLAIR)...

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Main Authors: Schreiner, Simon J., Liu, Xinyang, Gietl, Anton F., Wyss, Michael, Steininger, Stefanie C., Gruber, Esmeralda, Treyer, Valerie, Meier, Irene B., Kälin, Andrea M., Leh, Sandra E., Buck, Alfred, Nitsch, Roger M., Pruessmann, Klaas P., Hock, Christoph, Unschuld, Paul G.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2014
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159032/
https://ncbi.nlm.nih.gov/pubmed/25249977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2014.00240
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