Oxidant-Induced Activation of cGMP-Dependent Protein Kinase Iα Mediates Neuropathic Pain After Peripheral Nerve Injury

Aims: Emerging lines of evidence indicate that oxidants such as hydrogen peroxide exert specific signaling functions during the processing of chronic pain. However, the mechanisms by which oxidants regulate pain processing in vivo remain poorly understood. Here, we investigated whether cyclic guanos...

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Главные авторы: Lorenz, Jana E., Kallenborn-Gerhardt, Wiebke, Lu, Ruirui, Syhr, Katharina M.J., Eaton, Philip, Geisslinger, Gerd, Schmidtko, Achim
Формат: Artigo
Язык:Inglês
Опубликовано: Mary Ann Liebert, Inc. 2014
Предметы:
Original Research Communications
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4158966/
https://ncbi.nlm.nih.gov/pubmed/24450940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2013.5585
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