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The antiallodynic action of pregabalin may depend on the suppression of spinal neuronal hyperexcitability in rats with spared nerve injury

BACKGROUND: Pregabalin (PGB) is a novel antiepileptic drug and is also used as a first-line medication for the treatment of neuropathic pain. However, the mechanisms of its analgesic effects remain largely unknown. OBJECTIVES: To elucidate the mechanisms underlying the antiallodynic action of PGB in...

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Detalhes bibliográficos
Main Authors: Ding, Lei, Cai, Jie, Guo, Xiang-Yang, Meng, Xiu-Li, Xing, Guo-Gang
Formato: Artigo
Idioma:Inglês
Publicado em: Pulsus Group Inc 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4158936/
https://ncbi.nlm.nih.gov/pubmed/24851240
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