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miRNA-221 and miRNA-222 synergistically function to promote vascular calcification

Vascular calcification shares many similarities with skeletal mineralisation and involves the phenotypic trans-differentiation of vascular smooth muscle cells (VSMCs) to osteoblastic cells within a calcified environment. Various microRNAs (miRs) are known to regulate cell differentiation; however, t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mackenzie, N C W, Staines, K A, Zhu, D, Genever, P, MacRae, V E
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4158883/
https://ncbi.nlm.nih.gov/pubmed/24604335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbf.3005
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