High-Resolution Melting Curve Analysis, a Rapid and Affordable Method for Mutation Analysis in Childhood Acute Myeloid Leukemia

Background: Molecular genetic alterations with prognostic significance have been described in childhood acute myeloid leukemia (AML). The aim of this study was to establish cost-effective techniques to detect mutations of FMS-like tyrosine kinase 3 (FLT3), nucleophosmin 1 (NPM1), and a partial tande...

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Detalhes bibliográficos
Main Authors: Liu, Yin, Tang, Jingyan, Wakamatsu, Peter, Xue, Huiliang, Chen, Jing, Gaynon, Paul S., Shen, Shuhong, Sun, Weili
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Pediatrics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4158872/
https://ncbi.nlm.nih.gov/pubmed/25250304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fped.2014.00096
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