IL-4 and IL-13 Compromise the Sinonasal Epithelial Barrier and Perturb Intercellular Junction Protein Expression

INTRODUCTION: Altered expression of epithelial intercellular junction proteins has been observed in sinonasal biopsies from nasal polyps and epithelial layers cultured from nasal polyp patients. These alterations comprise a “leaky” epithelial barrier phenotype. We hypothesize that Th2 cytokines IL-4...

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Bibliographic Details
Main Authors: Wise, Sarah K., Laury, Adrienne M., Katz, Elizabeth H., Den Beste, Kyle A., Parkos, Charles A., Nusrat, Asma
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4158853/
https://ncbi.nlm.nih.gov/pubmed/24510479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/alr.21298
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