Unique mutation portraits and frequent COL2A1 gene alteration in chondrosarcoma

Chondrosarcoma is the second most frequent malignant bone tumor. However, the etiological background of chondrosarcomagenesis remains largely unknown, along with details on molecular alterations and potential therapeutic targets. Massively parallel paired-end sequencing of whole genomes of 10 primar...

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Détails bibliographiques
Auteurs principaux: Totoki, Yasushi, Yoshida, Akihiko, Hosoda, Fumie, Nakamura, Hiromi, Hama, Natsuko, Ogura, Koichi, Yoshida, Aki, Fujiwara, Tomohiro, Arai, Yasuhito, Toguchida, Junya, Tsuda, Hitoshi, Miyano, Satoru, Kawai, Akira, Shibata, Tatsuhiro
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2014
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4158757/
https://ncbi.nlm.nih.gov/pubmed/25024164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.160598.113
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