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The role of TASK1 in aldosterone production and its expression in normal adrenal and aldosterone-producing adenomas

OBJECTIVES: Aldosterone production in the adrenal glomerulosa is mainly regulated by angiotensin II and K(+). Adrenal glomerulosa cells are uniquely sensitive to extracellular K(+). Genetic deletion of subunits of K(+)-selective leak-channels (KCNK), TASK1 and/or TASK3, in mice generates animals wit...

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Detalhes bibliográficos
Main Authors: Nogueira, Edson F., Gerry, Daniel, Mantero, Franco, Mariniello, Barbara, Rainey, William E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4158746/
https://ncbi.nlm.nih.gov/pubmed/19878209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2265.2009.03738.x
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