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Evaluating empirical bounds on complex disease genetic architecture

The genetic architecture of human diseases governs the success of genetic mapping and the future of personalized medicine. Although numerous studies have queried the genetic basis of common disease, contradictory hypotheses have been advocated about features of genetic architecture (e.g., the contri...

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Detalhes bibliográficos
Main Authors: Agarwala, Vineeta, Flannick, Jason, Sunyaev, Shamil, Altshuler, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4158716/
https://ncbi.nlm.nih.gov/pubmed/24141362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2804
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