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Crucial role of calbindin-D(28k) in the pathogenesis of Alzheimer's disease mouse model
Calbindin-D(28k) (CB), one of the major calcium-binding and buffering proteins, has a critical role in preventing a neuronal death as well as maintaining calcium homeostasis. Although marked reductions of CB expression have been observed in the brains of mice and humans with Alzheimer disease (AD),...
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Main Authors: | , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4158683/ https://ncbi.nlm.nih.gov/pubmed/24853300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.67 |
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