Adequacy of a compartment model for CMRO(2) quantitation using (15)O-labeled oxygen and PET: a clearance measurement of (15)O-radioactivity following intracarotid bolus injection of (15)O-labeled oxyhemoglobin on Macaca fascicularis

We aimed at evaluating the adequacy of the commonly employed compartmental model for quantitation of cerebral metabolic rate of oxygen (CMRO(2)) using (15)O-labeled oxygen ((15)O(2)) and positron emission tomography (PET). Sequential PET imaging was carried out on monkeys following slow bolus inject...

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Detalhes bibliográficos
Main Authors: Iida, Hidehiro, Iguchi, Satoshi, Teramoto, Noboru, Koshino, Kazuhiro, Zeniya, Tsutomu, Yamamoto, Akihide, Kudomi, Nobuyuki, Moriguchi, Tetsuaki, Hori, Yuki, Enmi, Junichiro, Kawashima, Hidekazu, Joni Shah, Nadim, Nakagawara, Jyoji
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Rapid Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4158673/
https://ncbi.nlm.nih.gov/pubmed/25005879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2014.118
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