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Molecular cloning and expression of the 32-kDa subunit of human TFIID reveals interactions with VP16 and TFIIB that mediate transcriptional activation.

Transcription factor TFIID consists of TATA binding protein (TBP) and at least eight TBP-associated factors (TAFs). As TAFs are required for activated but not basal transcription, we have proposed that TAFs act as coactivators to mediate signals between activators and the basal transcription machine...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Klemm, R D, Goodrich, J A, Zhou, S, Tjian, R
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41586/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7597030/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.13.5788
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