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Response to Statin Therapy in Obstructive Sleep Apnea Syndrome: A Multicenter Randomized Controlled Trial

Rationale. Accumulated evidence implicates sympathetic activation as inducing oxidative stress and systemic inflammation, which in turn lead to hypertension, endothelial dysfunction, and atherosclerosis in obstructive sleep apnea (OSA). Statins through their pleiotropic properties may modify inflamm...

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Détails bibliographiques
Auteurs principaux: Joyeux-Faure, Marie, Tamisier, Renaud, Baguet, Jean-Philippe, Dias-Domingos, Sonia, Perrig, Stephen, Leftheriotis, Georges, Janssens, Jean-Paul, Trzepizur, Wojciech, Launois, Sandrine H., Stanke-Labesque, Françoise, Lévy, Patrick A., Gagnadoux, Frédéric, Pepin, Jean-Louis
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4158472/
https://ncbi.nlm.nih.gov/pubmed/25221387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/423120
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