Effect of Ranirestat, a New Aldose Reductase Inhibitor, on Diabetic Retinopathy in SDT Rats

Purpose. To evaluate the effect of ranirestat, a new aldose reductase inhibitor (ARI), on diabetic retinopathy (DR) in Spontaneously Diabetic Torii (SDT) rats. Methods. The animals were divided into six groups, normal Sprague-Dawley rats (n = 8), untreated SDT rats (n = 9), ranirestat-treated SDT ra...

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Main Authors: Toyoda, Fumihiko, Tanaka, Yoshiaki, Ota, Ayumi, Shimmura, Machiko, Kinoshita, Nozomi, Takano, Hiroko, Matsumoto, Takafumi, Tsuji, Junichi, Kakehashi, Akihiro
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4158328/
https://ncbi.nlm.nih.gov/pubmed/25215304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/672590
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