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Coding of stimulus strength via analog calcium signals in Purkinje cell dendrites of awake mice

The climbing fiber input to Purkinje cells acts as a teaching signal by triggering a massive influx of dendritic calcium that marks the occurrence of instructive stimuli during cerebellar learning. Here, we challenge the view that these calcium spikes are all-or-none and only signal whether the inst...

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Autors principals: Najafi, Farzaneh, Giovannucci, Andrea, Wang, Samuel S-H, Medina, Javier F
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4158287/
https://ncbi.nlm.nih.gov/pubmed/25205669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.03663
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