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Microglia P2Y(6) receptors mediate nitric oxide release and astrocyte apoptosis
BACKGROUND: During cerebral inflammation uracil nucleotides leak to the extracellular medium and activate glial pyrimidine receptors contributing to the development of a reactive phenotype. Chronically activated microglia acquire an anti-inflammatory phenotype that favors neuronal differentiation, b...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4158093/ https://ncbi.nlm.nih.gov/pubmed/25178395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-014-0141-3 |
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