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A Newfound Association between MDC1 Functional Polymorphism and Lung Cancer Risk in Chinese

Mediator of DNA damage checkpoint protein 1 (MDC1) plays an early and core role in Double-Strand Break Repair (DDR) and ataxia telangiectasia-mutated (ATM) mediated response to DNA double-strand breaks (DSBs), and thus involves the pathogenesis of several DNA damage-related diseases such as cancer....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wang, Bo, Zhang, Lisha, Qiu, Fuman, Fang, Wenxiang, Deng, Jieqiong, Zhou, Yifeng, Lu, Jiachun, Yang, Lei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4157800/
https://ncbi.nlm.nih.gov/pubmed/25198518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106794
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