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Ginsenoside 20(S)-Rg3 Targets HIF-1α to Block Hypoxia-Induced Epithelial-Mesenchymal Transition in Ovarian Cancer Cells

The prognosis of patients with ovarian cancer has remained poor mainly because of aggressive cancer progression. Since epithelial-mesenchymal transition (EMT) is an important mechanism mediating invasion and metastasis of cancer cells, targeting the EMT process with more efficacious and less toxic c...

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Bibliographic Details
Main Authors: Liu, Ting, Zhao, Le, Zhang, Yan, Chen, Wei, Liu, Dan, Hou, Huilian, Ding, Lu, Li, Xu
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4157750/
https://ncbi.nlm.nih.gov/pubmed/25197976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0103887
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