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An equilibrium model for linear and closed-loop amyloid fibril formation
Amyloid fibrils and their soluble oligomeric intermediates are implicated in several age-related diseases including Alzheimer’s and Parkinson’s disease. The distribution of oligomers and fibrils is related to toxicity and is dependent on the pathways for fibril assembly, generally considered to occu...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4157730/ https://ncbi.nlm.nih.gov/pubmed/22370559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.02.026 |
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