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The Spatial Organization of the VirR Boxes Is Critical for VirR-Mediated Expression of the Perfringolysin O Gene, pfoA, from Clostridium perfringens

The transcriptional regulation of toxin production in the gram-positive anaerobe Clostridium perfringens involves a two-component signal transduction system that comprises the VirS sensor histidine kinase and its cognate response regulator, VirR. Previous studies showed that VirR binds independently...

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Библиографические подробности
Главные авторы: Cheung, Jackie K., Dupuy, Bruno, Deveson, Deanna S., Rood, Julian I.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2004
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC415773/
https://ncbi.nlm.nih.gov/pubmed/15150217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.186.11.3321-3330.2004
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