Hepatic Localization of Macrophage Phenotypes during Fibrogenesis and Resolution of Fibrosis in Mice and Humans

Macrophages have been found to both promote liver fibrosis and contribute to its resolution by acquiring different phenotypes based on signals from the micro-environment. The best-characterized phenotypes in the macrophage spectrum are labeled M1 (classically activated) and M2 (alternatively activat...

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Dettagli Bibliografici
Autori principali: Beljaars, Leonie, Schippers, Marlies, Reker-Smit, Catharina, Martinez, Fernando O., Helming, Laura, Poelstra, Klaas, Melgert, Barbro N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2014
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4157549/
https://ncbi.nlm.nih.gov/pubmed/25250030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00430
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