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Spine pruning in 5xFAD mice starts on basal dendrites of layer 5 pyramidal neurons
Transgenic mice with Alzheimer’s disease (AD) mutations have been widely used to model changes in neuronal structure and function. While there are clear gross structural changes in post-mortem brains of AD patients, most mouse models of AD do not recapitulate the considerable loss of neurons. Furthe...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4157364/ https://ncbi.nlm.nih.gov/pubmed/23417057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00429-013-0518-6 |
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