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Sustained localized presentation of RNA interfering molecules from in situ forming hydrogels to guide stem cell osteogenic differentiation

To date, RNA interfering molecules have been used to differentiate stem cells on two-dimensional (2D) substrates that do not mimic three-dimensional (3D) microenvironments in the body. Here, in situ forming poly(ethylene glycol) (PEG) hydrogels were engineered for controlled, localized and sustained...

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Detalles Bibliográficos
Main Authors: Nguyen, Minh K., Jeon, Oju, Krebs, Melissa D., Schapira, Daniel, Alsberg, Eben
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4157362/
https://ncbi.nlm.nih.gov/pubmed/24831973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2014.04.048
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