Measuring diffusion limitation with a perfusion-limited gas—Hyperpolarized (129)Xe gas-transfer spectroscopy in patients with idiopathic pulmonary fibrosis

Although xenon is classically taught to be a “perfusion-limited” gas, (129)Xe in its hyperpolarized (HP) form, when detected by magnetic resonance (MR), can probe diffusion limitation. Inhaled HP (129)Xe diffuses across the pulmonary blood-gas barrier, and, depending on its tissue environment, shift...

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Hlavní autoři: Kaushik, S. Sivaram, Freeman, Matthew S., Yoon, Suk W., Liljeroth, Maria G., Stiles, Jane V., Roos, Justus E., Michael Foster, W. Sivaram, Rackley, Craig R., McAdams, H. P., Driehuys, Bastiaan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4157168/
https://ncbi.nlm.nih.gov/pubmed/25038105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00326.2014
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