Long-term obesity promotes alterations in diastolic function induced by reduction of phospholamban phosphorylation at serine-16 without affecting calcium handling

Few studies have evaluated the relationship between the duration of obesity, cardiac function, and the proteins involved in myocardial calcium (Ca(2+)) handling. We hypothesized that long-term obesity promotes cardiac dysfunction due to a reduction of expression and/or phosphorylation of myocardial...

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Main Authors: Lima-Leopoldo, Ana Paula, Leopoldo, André S., da Silva, Danielle C. T., do Nascimento, André F., de Campos, Dijon H. S., Luvizotto, Renata A. M., de Deus, Adriana F., Freire, Paula P., Medeiros, Alessandra, Okoshi, Katashi, Cicogna, Antonio C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4157165/
https://ncbi.nlm.nih.gov/pubmed/24970855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00088.2014
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