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Both Positive and Negative Effects on Immune Responses by Expression of a Second Class II MHC Molecule

It is perplexing why vertebrates express a limited number of Major Histocompatibility Complex (MHC) molecules when theoretically, having a greater repertoire of MHC molecules would increase the number of epitopes presented, thereby enhancing thymic selection and T cell response to pathogens. It is p...

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Detalhes bibliográficos
Main Authors: Ni, Peggy P., Wang, Yaming, Allen, Paul M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4157116/
https://ncbi.nlm.nih.gov/pubmed/25016574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2014.06.024
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