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The Effects of Tamoxifen in Combination with Tranilast on CXCL12-CXCR4 Axis and Invasion in Breast Cancer Cell Lines

It has been reported that CXCL12 binding to CXCR4 induces several intracellular signaling pathways, and enhances survival, proliferation, and migration of malignant cells. In the present study, we examined the effects of anti-estrogen tamoxifen and anti-allergic tranilast drugs as a single or in com...

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Detalhes bibliográficos
Main Authors: Darakhshan, Sara, Bidmeshkipour, Ali, Mansouri, Kamran, Saeid, Hakhamaneshi Mohammad, Ghanbari, Ali
Formato: Artigo
Idioma:Inglês
Publicado em: Shaheed Beheshti University of Medical Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4157045/
https://ncbi.nlm.nih.gov/pubmed/25237365
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